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The Dangers of Cannabis During Pregnancy - Cord Blood

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The Dangers of Cannabis During Pregnancy

Cannabis edibles

A recent study conducted by researchers at Oregon Health & Science University has found that consuming THC (the main active ingredient in cannabis) during pregnancy could have negative effects on fetal development and lead to long-term health problems for the child. Published in the journal Clinical Epigenetics, the research was carried out using a non-human primate model.

The Study

The researchers conducted a preclinical study using a non-human primate model to investigate the impact of THC on the placenta and the epigenome of the fetus. Epigenome refers to the chemical modifications to DNA that control gene expression. The researchers discovered that THC exposure resulted in changes to the genes responsible for regulating brain function, which are associated with conditions like autism spectrum disorder. Genes are vital codes responsible for various body and brain functions. Thus, any alteration to them, especially during pregnancy, is of concern. The study showed that THC could affect genes linked to neurobehavioral disorders like autism and ADHD.

The Risks

Lead author Lyndsey Shorey-Kendrick emphasized that despite the increasing popularity and availability of cannabis, it is not safe to use, particularly for certain populations, such as pregnant women. By better understanding the risks associated with THC use during pregnancy, healthcare providers can effectively communicate these risks to patients and promote safer habits during pregnancy.

Cannabis is gaining popularity in the US, and its use during pregnancy, especially in the first trimester to combat morning sickness, is on the rise. But the perception that it’s completely safe is challenged by this research.

The Findings

The study compared the effects of daily edible THC with a placebo in non-human primates. The researchers evaluated the impact on the placenta, fetal lung, brain, and heart. The results demonstrated that THC exposure altered the epigenome and genes associated with neurobehavioral disorders like autism spectrum disorder and attention deficit hyperactivity disorder. These conditions can lead to negative health outcomes in childhood and adolescence, including memory and cognitive issues, hyperactivity, impulsivity, and inattention.

Implications and Future Research

The research team hopes that these findings will contribute to the limited existing literature on THC use during pregnancy, enabling healthcare professionals to counsel patients and develop public health policies regarding cannabis. The study’s lead author Lyndsey Shorey-Kendrick, Ph.D. said, “The reality is that cannabis still carries many health risks for certain populations, including those who are pregnant. If we’re able to better understand the impacts, we can more effectively communicate the risks to patients and support safer habits during the vulnerable prenatal period.”

Conclusion

This study sheds light on the potential dangers of using THC during pregnancy, emphasizing the need for caution and understanding. It is crucial to inform women about the risks associated with cannabis use during pregnancy to protect the health and development of their children.