Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the ona domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /home/risezcom/public_html/cord-blood.org.uk/wp-includes/functions.php on line 6170
Scientists Create the First "Micro-Placenta" - Cord Blood

Cord Blood

and Stem Cell Banking

Scientists Create the First “Micro-Placenta”

Scientist testing stem cells

Scientists at Dundee University have developed a miniature placenta in the lab using stem cells, which could revolutionize research into pregnancy-related conditions.

The three-dimensional iPlacenta is grown on chips the size of a SIM card, using stem cells derived from human skin that are modified to become placenta cells. This breakthrough technology allows researchers to study the effects of drugs, toxins, and particles such as microplastics on cell lines that mimic the organ, without risking harm to the mother or fetus.

The team hopes that this development will lead to breakthroughs in treating conditions like intra-uterine growth restriction and pre-eclampsia, which can be life-threatening for both mother and baby. Currently, most placenta research is conducted using tissue collected after birth or using cell lines derived from cancer cells, but these methods are not ideal.

The iPlacenta will enable researchers to study the placenta’s early stages, where diseases and complications often occur. This is important because the placenta at delivery is very different from the placenta in these early stages.

The placenta is one of the least studied organs in medical science, despite its vital role in providing nutrients to the fetus and removing waste from the mother’s bloodstream. Clinical drug trials involving pregnant women are rare due to safety concerns. Limited treatments like aspirin and early deliveries are currently available if complications arise during pregnancy.

The iPlacenta was created in collaboration with Dutch 3D tissue model experts, MIMETAS. The placenta cells were grown on chips the size of a SIM card, forming 3D tubes covered by the placenta cells. Drugs and substances can be added to these tubes to measure their effects on the placenta barrier and function. This information can help determine their potential impact on the developing fetus.

The next step for the researchers is to secure funding for further trials and use the iPlacenta to study the interaction between drugs and the placenta. The pharmaceutical industry could benefit from this technology, as it allows for a more accurate understanding of how drugs interact with the organ. Ultimately, this could significantly improve medical care for pregnant women.

This groundbreaking development in placenta research is a source of pride for the scientists involved, as it has the potential to enhance women’s health and advance our understanding of pregnancy-related conditions.